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Pascal Loyer Selected Research

poly(malic acid)

4/2021Synthesis of Poly(Malic Acid) Derivatives End-Functionalized with Peptides and Preparation of Biocompatible Nanoparticles to Target Hepatoma Cells.
7/2017Poly(malic acid) bearing Doxorubicin and N-Acetyl Galactosamine as a site-specific prodrug for targeting hepatocellular carcinoma.
11/2016Opsonisation of nanoparticles prepared from poly(β-hydroxybutyrate) and poly(trimethylene carbonate)-b-poly(malic acid) amphiphilic diblock copolymers: Impact on the in vitro cell uptake by primary human macrophages and HepaRG hepatoma cells.
2/2012New functional degradable and bio-compatible nanoparticles based on poly(malic acid) derivatives for site-specific anti-cancer drug delivery.

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Pascal Loyer Research Topics

Disease

17Hepatocellular Carcinoma (Hepatoma)
06/2022 - 09/2003
12Neoplasms (Cancer)
11/2020 - 09/2003
3Iron Overload
04/2004 - 01/2002
1Chronic Obstructive Pulmonary Disease (COPD)
01/2020
1Alcoholic Fatty Liver
02/2019
1Gout
02/2019
1Inflammation (Inflammations)
02/2019
1Pulmonary Fibrosis (Fibrosing Alveolitis)
02/2019
1Hypertrophy
01/2018
1Cachexia
11/2015
1Acquired Immunodeficiency Syndrome (AIDS)
09/2015
1Virus Diseases (Viral Diseases)
01/2015
1Wounds and Injuries (Trauma)
01/2012
1Hypoxia (Hypoxemia)
11/2009
1Colorectal Neoplasms (Colorectal Cancer)
08/2009
1Colonic Neoplasms (Colon Cancer)
08/2009
1Hemochromatosis (Bronze Diabetes)
07/2003
1Liver Failure
12/2002

Drug/Important Bio-Agent (IBA)

9Pharmaceutical PreparationsIBA
07/2020 - 09/2003
6Proteins (Proteins, Gene)FDA Link
06/2022 - 10/2013
4Peptides (Polypeptides)IBA
06/2022 - 10/2013
4poly(malic acid)IBA
04/2021 - 02/2012
4EnzymesIBA
05/2019 - 11/2009
3Biotin (Vitamin H)FDA Link
04/2022 - 02/2012
3poly(benzyl malate)IBA
04/2022 - 02/2012
3Ethanol (Ethyl Alcohol)IBA
08/2020 - 11/2009
3XenobioticsIBA
05/2019 - 09/2003
3Doxorubicin (Adriamycin)FDA LinkGeneric
07/2017 - 02/2012
3IronIBA
04/2004 - 01/2002
2StreptavidinIBA
04/2022 - 10/2013
2LigandsIBA
04/2022 - 02/2012
1maleimideIBA
06/2022
1Ethylene Glycol (Monoethylene Glycol)IBA
04/2022
1ApolipoproteinsIBA
04/2022
1CyclinsIBA
11/2020
1Fluorine-18IBA
09/2020
1Somatostatin (Somatotropin Release-Inhibiting Factor)IBA
09/2020
1Indium-111IBA
09/2020
1Technetium-99IBA
09/2020
1Gallium-68IBA
09/2020
1Copper-64IBA
09/2020
1AcidsIBA
07/2020
1Interleukin-4 (Interleukin 4)IBA
01/2020
1CytokinesIBA
01/2020
1SmokeIBA
01/2020
1InflammasomesIBA
02/2019
1Purinergic Receptors (Receptors, Purine)IBA
02/2019
1Purinergic P2X7 ReceptorsIBA
02/2019
1mahuang-tangIBA
01/2018
1macro aggregates of albuminIBA
01/2018
1GalactosamineIBA
07/2017
1ProdrugsIBA
07/2017
1erucylphosphocholineIBA
05/2017
1Liposomes (Liposome)IBA
05/2017
1polytrimethylene carbonateIBA
11/2016
1cardiolipin synthetaseIBA
04/2016
1Cardiolipins (Cardiolipin)IBA
11/2015
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
11/2015
1cyclic arginine-glycine-aspartic acid peptideIBA
10/2013
1biotin receptorIBA
10/2013
12-methylcyclopentadienyl manganese tricarbonyl (MMT)IBA
02/2012
1Fluorescent Dyes (Fluorescent Probes)IBA
02/2012
12- amino- 1- methyl- 6- phenylimidazo(4,5- b)pyridineIBA
11/2010
1Cytochrome P-450 CYP3AIBA
11/2009
1LipidsIBA
11/2009
1Amino AcidsFDA Link
11/2009
1Oxygen (Dioxygen)IBA
11/2009
1Testosterone (Sustanon)FDA Link
11/2009
1dimethylethylsilylimidazoleIBA
11/2009
1Paclitaxel (Taxol)FDA LinkGeneric
11/2009
1Cytotoxins (Cytolysins)IBA
11/2009
1CytochromesIBA
11/2009
1Multidrug Resistance-Associated ProteinsIBA
08/2009
1Fluorouracil (Carac)FDA LinkGeneric
08/2009
1CD226 antigenIBA
05/2009
1DeferiproneIBA
04/2004
1Chelating AgentsIBA
04/2004
1trichostatin A (A 300)IBA
09/2003
1theasinensin AIBA
09/2003
1Caspase 8 (Caspase-8)IBA
12/2002
1CaspasesIBA
12/2002
1Caspase 3 (Caspase-3)IBA
12/2002
1Thioacetamide (Thioacetamid)IBA
12/2002
1Protein Isoforms (Isoforms)IBA
01/2002

Therapy/Procedure

5Therapeutics
04/2021 - 09/2003
1Precision Medicine
04/2021
1Microspheres (Microsphere)
01/2018
1Hepatectomy
01/2015
1Drug Therapy (Chemotherapy)
11/2009